Where Should You Go For Houston Stem Cell Therapy?

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Stem Cell Therapy for Pain Management

Currently, the most popular form of stem cell therapy is bone marrow transplant. However, the regenerative properties of stem cells also make them ideal for treating arthritis, chronic pain, and injuries leading to chronic pain and even autoimmunity. So, the scope of stem cell therapy-based treatments is vast. Let us now tell you in greater detail about how Houston stem cell therapy can help you recover from illnesses and accidents and lead a pain-free life:

Arthritis affects a major chunk of the US population. It is a debilitating disease that has a considerable impact on the quality of life of patients. While there are some treatments that are available for arthritis, most require early detection and invasive surgeries. Even then, the chances of alleviating pain are not very high. In this regard, Houston stem cell therapy can provide a great alternative to arthritis patients. A minimally invasive injection of stem cells into joints can help immensely in returning the body part to normal, pain-free functioning.

There can be many reasons for the rise of chronic pain the human body. Aging, illnesses and unfortunate accidents are some of the most frequent reasons. Normally, treatment for chronic pain involves the combined uses of drugs, surgery and rehabilitative therapy. But these are only marginally effective and cannot address the pain as definitively as stem cell therapy. Because stem cells have the unique property of transforming into whatever type of cells required by the body, they can be used to help patients regenerate their damaged body parts. This can potentially lead to a radical alleviation of chronic pain.

Thanks to the major influx and wide use of pharmaceuticals in the US, autoimmune diseases have become widespread. Most of them still do not have any treatments and as a result, patients are left to suffer and sometimes even die from them. However, Houston stem cell therapy has proven to be a very useful way of addressing autoimmune diseases. By helping the body naturally replace errant cells with healthy ones, stem cell therapy can not only treat autoimmune conditions but also vastly enhance the patient’s quality of life.

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Houston Stem Cell Therapy: Understand How it Can Help You With Body Pain

Medical science is developing at an immense pace. Now, we have treatments for diseases that were earlier thought to be incurable. One of the most popular new medical treatment methods is stem cell therapy. Arguably one of the most promising new treatment methods to emerge of late, it could very well transform the way we live.

Houston Stem Cell Health Center in River Oaks Medical Tower

Conditions

Here is a list of health conditions where stem cell therapy may help.

ALS

19 amyotrophic lateral sclerosis (ALS) patients receiving stem cell treatment intrathecally, Amyotrophic Lateral Sclerosis Functional Rating Scale score remained stable for 6 months after intervention, and Expanded Disability Status Scale scores improved from 6.7 to 5.9 on average. (Source: Karussis D. et al; Archive of Neurology 2010; 67: 1187–1194.)

Alzheimer’s

Potentially of greater therapeutic significance are the reported neuroprotective paracrine effects of Mesenchymal Stem Cells (MSCs), with the introduction of MSC-secreted factors able to stimulate proliferation, neuronal differentiation, and survival in endogenous neurogenic niches for Alzheimer’s Disease. (Source: Teixeira FG, et al; Stem Cell Rev Rep. 2015;11:288–97.)

Anti-Aging and Apoptosis

One of the important property of MSCs is the ability to rescue apoptotic cells induced by
traumatic exposures to hypoxia, chemicals/acidity, mechanical damage and radiation. For example, MSCs have proved to reverse apoptosis in cardiomyoblasts after ischemia, as well as
damaged neurons and lung fibroblasts. (Source: Cselenya´k et al; BMC Cell Biol 2010; 11: 29.)

Autoimmune Disease

Based on their ability to modulate immune responses, MSCs are the best stem cells as a treatment for autoimmune diseases. Patients suffering from severe autoimmune diseases do not respond to standard therapy and can be treated with autologous or allogenic MSC therapy. The clinical significance of MSCs mainly contribute to its potent immunosuppressive and anti-inflammatory effects through the interactions between the lymphocytes associated with both the innate and adaptive immune systems. MSCs suppress activities such as T-cell proliferation, B-cell functions, natural killer cell proliferation, and cytokine production and prevent the differentiation, maturation, and activation of dendritic cells. (Biointegration of Medical Implant Materials (Second Edition), Woodhead Publishing Series in Biomaterials 2020)

Crohn’s Disease

Crohn’s disease is an inflammatory bowel disease (IBD). It causes inflammation of your digestive tract, which can lead to a variety of symptoms. Twelve patients with Fistulising Crohn’s disease were treated with intra fistular injection of MSC stem cell and achieved sustained complete closure of fistula tracks in seven cases and partial closure in three cases. Rectal mucosa healing was observed in all patients, as well as a significant increase in circulating Treg cells. (Source: Ciccocioppo R, et al. Gut 2011; 60:788–798.)

Diabetes
(Type 1 & 2)

Type 1 diabetes is an autoimmune disease mediated by the production of autoantibody directed against the b cells of the pancreas. Studies on umbilical cord blood (UCB)e derived MSCs that demonstrated the expression of pancreatic development genes in these cells. Recently, a population of UCB-derived cells was shown to behave like hES cells, recapitulating the same differentiation steps from early stages to b-cells (Inverardi et al., 2003; Prabakar et al., 2011). Meanwhile we have seen most of type 2 diabetes patients’ HA1C have drop down below 6.0 under our comprehensive care.

Heart Failure

Heart failure is a condition in which the heart can’t pump enough blood throughout the body. In an heart failure clinical study, the lowest dose of stem cells (25 million) resulted in the greatest improvement in LV ejection fraction and LV systolic volume, whereas no significant effect was achieved by 75 or 150 million stem cell doses at 3, 6 or 12 months.
(Source: Perin EC, et al 2011 Scientific Sessions of the American Heart Association. 14, November 2011; Orlando, FL, 2011.)

Kidney Disease

Majority of our patients, who are suffering from Stage 5 or 4 or 3 kidney disease, have seen improvement of their kidney function, ie. eGFR improved and reduced blood BUN and Creatinine at weMED Health Center. A recent systematic review of over 70 articles highlighted MSCs as one of the most effective cell populations for treating experimental chronic kidney disease. (Papazova D.A., et al, Dis. Model. Mech. 2015;8:281–293.

Knee Osteoarthritis

MSC Stem Cell transplantation has been shown to produce significant clinical improvements with cartilage repair. The transplanted MSCs can be differentiated into chondrocytes, or it is also possible that MSCs produce soluble growth factors to induce other cells of the microenvironment to differentiate into cartilage. Most of weMED Health Patients whose before and after x-rays have showed regrowth of cartilage and significant relief of symptoms. See more of our patients before and after X-rays…

Liver Disease

Quite a few clinical research demonstrated the effectiveness and safety of stem cell treating liver diseases. In a clinical trial, Zhang et al. administered a dosage of 0.5106/kg body weight HUC-MSCs in 30 patients with decompensated liver cirrhosis. The cells were infused intravenously three times at 4-week intervals. After 40-week follow-up, there was a significant reduction in the volume of ascites and improvement in liver function in all of the HUC-MSCs treated patients. No adverse effects were reported in any patient during the follow-up. (Source: Zhang Z, et al. Journal of Gastroenterology and Hepatology 2012;27(Suppl 2):112-20)

Lupus

The most recent evidence in favor of MSC-based treatment of SLE involves 15 refractory-stage SLE patients. Significant improvements were seen in systemic lupus erythematosus disease activity index (SLEDAI) scores, and proteinuria and stabilization of renal function after 12 months. (Source: Sun L, et al. Stem Cells 2009; 27: 1421–1432.)

Lyme Disease

Also known as Lyme borreliosis, is an infectious disease caused by the Borrelia bacterium which is spread by ticks.

Multiple Sclerosis

MSCs have pronounced immune-modulating and immunosuppressive properties so as they were being tested in clinical trial for relapsing-remitting multiple sclerosis. MSCs promote self-repair by reducing scar formation, by stimulating the formation of new blood vessel, and by secreting growth and neuroprotective factors, such as superoxide dismutase-3. After intravenous injection, many cells entered the CNS and became widely distributed both in experimental models and in patients (Prockop and Youn Oh, 2012; Uccelli et al., 2007)

Neuropathy

Regardless the causes of neuropathy, such as by diabetes, chemotherapy-induced or age-related, weMED comprehensive treatment, which addressing the nerve damage and causes, has provided significant improvement for patients’ feet and hands, as well as balance.

Parkinson’s Disease

Stem cell therapy, with the aim of replacing lost neurons, is the most promising strategy for this disease. It has been demonstrated that MSCs cells can enhance the levels of tyrosine hydroxylase and dopamine after transplantation in PD (parkinson’s disease). Furthermore, it has been suggested that these cells contribute to neuro-protection by secreting trophic factors, such as EGF, VEGF, NT3, FGF-2, HGF, and BDNF, or through antiapoptotic signaling without differentiation in neuronal pheno-type. (Wang et al., 2010; Wilkins et al., 2009;Moloney et al., 2010

Rheumatoid arthritis

weMED has seen great success in treating RA patients, clinical study from Zheng et al. demonstrated that MSCs isolated from RA patients exerted immunosuppressive functions, by inhibiting T-cell proliferation, blocking the secretion of several proinflammatory cytokines, and allowing the expression of antiinflammatory IL-10. (Zheng et al., 2008; Augello et al., 2007; Maoet al., 2010).

Spinal Cord Injury

Damage to the spinal cord that may cause temporary or permanent changes to its function. Four patients (80%) receiving stem cells improved from Grade A to Grade C, and one patient improved from Grade A to Grade B. The GCSF-only patient remained at Grade A. The only side effects observed were fever and myalgia. (Source: Park H, et al. Tissue Engineering 2005; 11: 913–922.)

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